人微管相關(guān)蛋白Tau-4單克隆抗體
- 發(fā)布日期: 2023-11-21
- 更新日期: 2025-10-10
產(chǎn)品詳請
產(chǎn)地 |
上海
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品牌 |
森興研
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保存條件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
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貨號 |
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用途 |
科研
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應(yīng)用范圍 |
WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:400-800 (石蠟切片需做抗原修復) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
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抗原來源 |
Mouse
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保質(zhì)期 |
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抗體名 |
Tau-4
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是否單克隆 |
是
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克隆性 |
是
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靶點 |
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適應(yīng)物種 |
咨詢
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形態(tài) |
Liquid
|
宿主 |
咨詢
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標記物 |
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包裝規(guī)格 |
100ul
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亞型 |
IgG
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標識物 |
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濃度 |
1mg/ml%
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免疫原 |
Recombinant Human Tau-4 Protein: 1-441/441
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是否進口 |
否
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研究領(lǐng)域細胞生物 免疫學 神經(jīng)生物學 信號轉(zhuǎn)導
抗體來源Mouse
克隆類型Monoclonal
交叉反應(yīng)Human, Mouse, Rat,
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:400-800 (石蠟切片需做抗原修復)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量46/79kDa
性 狀Liquid
濃 度1mg/ml
免 疫 原Recombinant Human Tau-4 Protein: 1-441/441
亞 型IgG
純化方法affinity purified by Protein A
緩 沖 液0.01M PBS(pH7.4)
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事項This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMedPubMed
產(chǎn)品介紹Tau proteins are important Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. Tau proteins subcellular located in the axons of neurons, in the cytoso l and in association with plasma membrane components. It expressed in neurons. PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.
SWISS:
P10636-8
Gene ID:
4137