Ki67蛋白抗體
- 發(fā)布日期： 2023-11-21
- 更新日期： 2025-10-10
產品詳請
| 產地 |
上海
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| 品牌 |
森興研
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| 保存條件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
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| 貨號 |
|
| 用途 |
科研
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| 應用范圍 |
IHC-P=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
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| 抗原來源 |
Mouse
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| 保質期 |
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| 抗體名 |
Ki-67
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| 是否單克隆 |
是
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| 克隆性 |
是
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| 靶點 |
|
| 適應物種 |
咨詢
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| 形態(tài) |
Liquid
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| 宿主 |
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| 標記物 |
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| 包裝規(guī)格 |
100ul
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| 亞型 |
IgG
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| 標識物 |
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| 濃度 |
1mg/ml%
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| 免疫原 |
Recombinant human Ki-67
|
| 是否進口 |
否
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英文名稱Ki-67
中文名稱Ki67蛋白抗體
別 名Antigen identified by monoclonal antibody Ki 67; Antigen KI67; KIA; Ki67; MKI67; Proliferation related Ki 67 antigen; Antigen KI-67; KI67_HUMAN.
研究領域腫瘤 細胞生物 神經生物學 細胞周期蛋白 細胞分化 細胞類型標志物
抗體來源Mouse
克隆類型Monoclonal
交叉反應Human, Mouse, Rat,
產品應用IHC-P=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量358kDa
細胞定位細胞核
性 狀Liquid
濃 度1mg/ml
免 疫 原Recombinant human Ki-67
亞 型IgG
純化方法affinity purified by Protein G
緩 沖 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事項This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMedPubMed
產品介紹Ki67 antigen is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 antibodies are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67 index and histologically low grade tumours is strong. Ki67 is routinely used as a neuronal marker of cell cycling and proliferation.
Function:
Thought to be required for maintaining cell proliferation.
Subcellular Location:
Nucleus. Chromosome. Predominantly localized in the G1 phase in the perinucleolar region, in the later phases it is also detected throughout the nuclear interior, being predominantly localized in the nuclear matrix. In mitosis, it is present on all chromosomes.
Similarity:
Contains 1 FHA domain.
SWISS:
P46013
Gene ID:
4288
