突觸小泡蛋白P38重組兔單抗
- 發布日期： 2023-11-20
- 更新日期： 2025-10-10
產品詳請
| 產地 |
上海
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| 品牌 |
森興研
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| 保存條件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
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| 貨號 |
|
| 用途 |
科研
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| 應用范圍 |
WB=1:500-2000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50 IF=1:50-200 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
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| 抗原來源 |
Rabbit
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| 保質期 |
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| 抗體名 |
Synaptophysin
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| 是否單克隆 |
是
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| 克隆性 |
是
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| 靶點 |
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| 適應物種 |
咨詢
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| 形態 |
Liquid
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| 宿主 |
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| 標記物 |
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| 包裝規格 |
100ul
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| 亞型 |
IgG
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| 標識物 |
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| 濃度 |
1mg/ml%
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| 免疫原 |
Recombinant human SYP protein: 210-313/313
|
| 是否進口 |
否
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英文名稱Synaptophysin
中文名稱突觸小泡蛋白P38重組兔單抗
別 名Major synaptic vesicle protein P38; MRXSYP; Syn p38; SYP; SYPH; SYPH_HUMAN; SypI.
研究領域細胞生物 神經生物學
抗體來源Rabbit
克隆類型Monoclonal
克 隆 號2B1
交叉反應Human, Mouse, Rat,
產品應用WB=1:500-2000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50 IF=1:50-200 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量34kDa
細胞定位細胞漿
性 狀Liquid
濃 度1mg/ml
免 疫 原Recombinant human SYP protein: 210-313/313
亞 型IgG
純化方法affinity purified by Protein A
緩 沖 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事項This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMedPubMed
產品介紹This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with X-linked mental retardation (XLMR). [provided by RefSeq, Aug 2011]
Function:
Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity.
Subcellular Location:
Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane. Cell junction > synapse > synaptosome.
Tissue Specificity:
Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype.
Post-translational modifications:
Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation.
DISEASE:
Defects in SYP are the cause of mental retardation X-linked SYP-related (MRXSYP) [MIM:300802]. Mental retardation is characterized by significantly below average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period.
Similarity:
Belongs to the synaptophysin/synaptobrevin family. Contains 1 MARVEL domain.
SWISS:
P08247
Gene ID:
6855
