胰島素基因增強結合蛋白1抗體
- 發布日期： 2023-11-17
- 更新日期： 2025-10-10
產品詳請
| 產地 |
上海
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| 品牌 |
森興研
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| 保存條件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
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| 貨號 |
|
| 用途 |
科研
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| 應用范圍 |
WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
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| 抗原來源 |
Rabbit
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| 保質期 |
6
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| 抗體名 |
Islet-1
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| 是否單克隆 |
否
|
| 克隆性 |
是
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| 靶點 |
|
| 適應物種 |
咨詢
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| 形態 |
Liquid
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| 宿主 |
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| 標記物 |
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| 包裝規格 |
100ul
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| 亞型 |
IgG
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| 標識物 |
|
| 濃度 |
1mg/1ml%
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| 免疫原 |
KLH conjugated synthetic peptide derived from human Islet-1: 51-150/349
|
| 是否進口 |
否
|
英文名稱Islet-1
中文名稱胰島素基因增強結合蛋白1抗體
別 名Insulin gene enhancer protein ISL 1; Insulin gene enhancer protein ISL-1; Insulin related protein; Isl 1; ISL LIM homeobox 1; ISL1; ISL1 transcription factor LIM homeodomain; ISL1 transcription factor, LIM/homeodomain (islet 1); ISL1 transcription factor, LIM/homeodomain; ISL1_HUMAN; Islet-1; Islet1.
研究領域心血管 細胞生物 神經生物學 信號轉導 干細胞 細胞類型標志物
抗體來源Rabbit
克隆類型Polyclonal
交叉反應Human, Mouse, Rat, (predicted: Cow, Horse, Sheep, )
產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量39kDa
細胞定位細胞核
性 狀Liquid
濃 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human Islet-1: 51-150/349
亞 型IgG
純化方法affinity purified by Protein A
緩 沖 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事項This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMedPubMed
產品介紹This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. [provided by RefSeq, Jul 2008].
Function:
Binds to one of the cis-acting domain of the insulin gene enhancer.
Subcellular Location:
Nucleus.
Tissue Specificity:
Expressed in subsets of neurons of the adrenal medulla and dorsal root ganglion, inner nuclear and ganglion cell layers in the retina, the pineal and some regions of the brain.
Similarity:
Contains 1 homeobox DNA-binding domain.
Contains 2 LIM zinc-binding domains.
SWISS:
P61371
Gene ID:
3670
