細胞角蛋白7抗體
- 發布日期： 2023-11-16
- 更新日期： 2025-10-10
產品詳請
| 產地 |
上海
|
| 品牌 |
森興研
|
| 保存條件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
|
| 貨號 |
|
| 用途 |
可以
|
| 應用范圍 |
WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=0.2μg/Test IF=1:100-500 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
|
| 抗原來源 |
Rabbit
|
| 保質期 |
|
| 抗體名 |
CK7
|
| 是否單克隆 |
否
|
| 克隆性 |
是
|
| 靶點 |
|
| 適應物種 |
咨詢
|
| 形態 |
Liquid
|
| 宿主 |
|
| 標記物 |
|
| 包裝規格 |
100ul
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| 亞型 |
IgG
|
| 標識物 |
|
| 濃度 |
1mg/ml%
|
| 免疫原 |
KLH conjugated synthetic peptide derived from the middle of human CK7: 251-350/469
|
| 是否進口 |
否
|
研究領域信號轉導
抗體來源Rabbit
克隆類型Polyclonal
交叉反應Human, Mouse, Rat,
產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=0.2μg/Test IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量54kDa
細胞定位細胞漿
性 狀Liquid
濃 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from the middle of human CK7: 251-350/469
亞 型IgG
純化方法affinity purified by Protein A
緩 沖 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事項This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMedPubMed
產品介紹The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]
Function:
Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).
Subunit:
Heterotetramer of two type I and two type II keratins. Interacts with eukaryotic translation initiator factor 3 (eIF3) subunit EIF3S10 and with HPV16 E7.
Subcellular Location:
Cytoplasm.
Tissue Specificity:
Expressed in cultured epidermal, bronchial and mesothelial cells but absent in colon, ectocervix and liver. Observed throughout the glandular cells in the junction between stomach and esophagus but is absent in the esophagus.
Post-translational modifications:
Arg-20 is dimethylated, probably to asymmetric dimethylarginine.
Similarity:
Belongs to the intermediate filament family.
SWISS:
P08729
Gene ID:
3855
