富含半胱氨酸的酸性分泌蛋白抗體
- 發布日期： 2023-11-15
- 更新日期： 2025-10-10
產品詳請
| 產地 |
上海
|
| 品牌 |
森興研
|
| 保存條件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
|
| 貨號 |
|
| 用途 |
|
| 應用范圍 |
WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=2ug/Test IF=1:100-500 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user
|
| 抗原來源 |
Rabbit
|
| 保質期 |
|
| 抗體名 |
SPARC
|
| 是否單克隆 |
否
|
| 克隆性 |
是
|
| 靶點 |
|
| 適應物種 |
咨詢
|
| 形態 |
Liquid
|
| 宿主 |
|
| 標記物 |
|
| 包裝規格 |
100ul
|
| 亞型 |
IgG
|
| 標識物 |
|
| 濃度 |
1mg/ml%
|
| 免疫原 |
KLH conjugated synthetic peptide derived from human SPARC: 101-200/303
|
| 是否進口 |
否
|
研究領域腫瘤 細胞生物 信號轉導 干細胞 細胞周期蛋白 細胞骨架 細胞外基質
抗體來源Rabbit
克隆類型Polyclonal
交叉反應Human, Mouse, Rat, (predicted: Dog, Pig, Cow, Horse, Rabbit, )
產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=2ug/Test IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量33kDa
細胞定位細胞膜 細胞外基質 分泌型蛋白
性 狀Liquid
濃 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human SPARC: 101-200/303
亞 型IgG
純化方法affinity purified by Protein A
緩 沖 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事項This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMedPubMed
產品介紹This gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion. [provided by RefSeq, Dec 2011].
Function:
Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
Subcellular Location:
Secreted, extracellular space, extracellular matrix, basement membrane. Note=In or around the basement membrane.
Similarity:
Belongs to the SPARC family.
Contains 1 EF-hand domain.
Contains 1 follistatin-like domain.
Contains 1 Kazal-like domain.
SWISS:
P09486
Gene ID:
6678
