絲/蘇氨酸蛋白激酶II β重組兔單抗
- 發布日期： 2023-11-08
- 更新日期： 2025-10-10
產品詳請
| 產地 |
上海
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| 品牌 |
森興研
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| 保存條件 |
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
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| 貨號 |
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| 用途 |
|
| 應用范圍 |
WB=1:500-2000 IP=1:10-50 IHC-P=1:50-100 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user
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| 抗原來源 |
Rabbit
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| 保質期 |
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| 抗體名 |
CSNK2B/CK II beta
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| 是否單克隆 |
是
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| 克隆性 |
是
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| 靶點 |
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| 適應物種 |
咨詢
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| 形態 |
Liquid
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| 宿主 |
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| 標記物 |
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| 包裝規格 |
100ul
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| 亞型 |
IgG
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| 標識物 |
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| 濃度 |
1mg/ml%
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| 免疫原 |
KLH conjugated synthetic peptide derived from human CSNK2B/CK II beta
|
| 是否進口 |
否
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英文名稱CSNK2B/CK II beta
中文名稱絲/蘇氨酸蛋白激酶II β重組兔單抗
別 名Casein kinase 2 beta polypeptide; casein kinase IIβ; Casein kinase II subunit beta; CK II beta; CK2B; CK2N; CSK2B; CSK2B_HUMAN; CSNK 2B; CSNK2B; G5A; MGC138222; MGC138224; Phosvitin; Protein G5a.
研究領域腫瘤 細胞生物 信號轉導 干細胞 細胞周期蛋白 轉錄調節因子 激酶和磷酸酶
抗體來源Rabbit
克隆類型Monoclonal
克 隆 號2C9
交叉反應Human, Mouse, Rat,
產品應用WB=1:500-2000 IP=1:10-50 IHC-P=1:50-100 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量25kDa
細胞定位細胞核 細胞漿 細胞膜 細胞外基質 分泌型蛋白
性 狀Liquid
濃 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human CSNK2B/CK II beta
亞 型IgG
純化方法affinity purified by Protein A
緩 沖 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事項This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMedPubMed
產品介紹This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus. [provided by RefSeq, Jul 2008].
Function:
Participates in Wnt signaling. Plays a complex role in regulating the basal catalytic activity of the alpha subunit.
Subunit:
Tetramer composed of an alpha subunit, an alpha' subunit and two beta subunits. The beta subunit dimerization is mediated by zinc ions. Interacts with TCTEX1D3 (By similarity). Interacts with CD163. Also component of a CK2-SPT16-SSRP1 complex composed of SSRP1, SUPT16H, CSNK2A1, CSNK2A2 and CSNK2B, the complex associating following UV irradiation. Interacts with MUSK; mediates phosphorylation of MUSK by CK2.
Post-translational modifications:
Phosphorylated by alpha subunit.
Similarity:
Belongs to the casein kinase 2 subunit beta family.
SWISS:
P67871
Gene ID:
1460
